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Genetic Testing

Cancer Prevention, Hereditary Genetics, and Epidemiology

2019 ASCO Annual Meeting

Sort by: title abstract no. first author
ABSTRACT TITLEFIRST AUTHORABSTRACT NO.
BRCA1/2 and multigene panel testing among metastatic breast, pancreas, prostate, and ovarian cancer patients.

Meghna S. Trivedi

e13160

A pan-cancer analysis of microsatellite instability as a predictor of Lynch syndrome in Chinese population.

Pinzhu Huang

1574

A pharmacogenetic analysis of peripheral sensory neuropathy related to administration of taxanes in breast cancer patients.

Alyson Leonard

e13133

An optimized workflow for a fast molecular diagnosis of non-small cell lung cancer.

Bing Wei

e13139

Auxiliary diagnosis of pulmonary nodules using liquid biopsy and deep learning/techniques.

Li Bai

e13154

Blood-based genomic profiling of circulating tumor DNA from patients with advanced biliary tract cancer.

Junying Wang

1576

Characterization of genomic alterations in Chinese LCNEC and SCLC via comprehensive genomic profiling.

Lin Wu

1575

Clinical significance of pathogenic variants in germline BRCA wild type patients at risk for hereditary breast cancer.

Xiaying Kuang

e13127

Combinational analysis of IDH1/IDH2 mutations, 1p/19q deletions and MGMT promoter methylation for molecular testing of glioma.

Xiaoni Zhang

e13152

Comprehensive germline multigene panel testing changes clinical care for patients with breast cancer: Untapped clinical utility and PARP inhibitor trial eligibility.

Peter D. Beitsch

1583

Co-occurring genetic alterations and primary EGFR T790M mutations detected by next-generation sequencing in pre-TKI treated patients with non-small cell lung cancer.

Yuan Tang

e13128

Correlation of negative PD-L1 expression with TMB-H and MSI-H rates.

Jun Dong

e13162

Determination of the immunogenetic risk of developing cancer.

István Miklós

e13132

Differences in MSI phenotype between cancer types using a new PCR-based pan-cancer biomarker panel.

Jeff Bacher

e13145

Disparities in pretest genetic counseling among a population-based sample of young breast cancer patients.

Sonya Reid-Lawrence

1579

DNA Input, sequencing depth, and maximum somatic allele frequency may affect the concordance between blood TMB and tumor TMB.

Yuqing Huang

e13163

Do genetic testing criteria identify individuals with Lynch syndrome prior to cancer diagnoses?

Brian Reys

e13158

Early non-invasive detection of stage Ia lung cancer using circulating tumor DNA methylation haplotypes (ctmDNA) in plasma.

Kun Zhang

e13159

Early results from the BRCA Founder Outreach (BFOR) Study: Population genetic screening using a medical model.

Kelly Morgan

1578

EMR documentation of genetics evaluations in patients with ovarian cancer.

Payal Deepak Shah

e13156

Enhanced family history screening is crucial to individualized cancer surveillance.

Kristin Clift

e13161

Enhancing access to genetic cancer risk assessment (GCRA) in Monterrey, Mexico: The beginning of a prevention program.

Dione Aguilar y Méndez

e13150

Genetic testing for hereditary breast and ovarian cancer in Indian population: A single institutional study.

Veda Padma Priya Selvakumar

e13153

Genomic alteration features of six cancers and their correlation with clinical characters using the next generation sequencing.

Qian Dong

e13130

Genomic profiling for unfavorable carcinoma of unknown primary patients.

Hsueh-Ju Lu

e13140

Genomic profiling of pulmonary lymphoepithelioma-like carcinoma (PLELC).

Chengzhi Zhou

1572

Genomic testing and treatment landscape in patients with advanced non-small cell lung cancer (aNSCLC) using real-world data from community oncology practices.

Hinco Jasper Gierman

1585

Germline analysis of DNA-damage repair genes in men with advanced prostate cancer in comparison to women with breast cancer.

Amy Kunz

e13147

Germline genetic testing in ovarian cancer patients: Identifying barriers to care and opportunities for improvement.

Elizabeth Stock

e13142

Germline mutation profile among Hispanic women with epithelial ovarian cancer (EOC).

Yanin Chavarri Guerra

1584

Implications of incidental germline findings identified in the context of clinical whole exome sequencing (WES) for guiding cancer therapy.

Bryan P. Schneider

1581

Molecular characterization of NSCLC-like and SCLC-like subsets in Chinese pulmonary large cell neuroendocrine carcinoma (LCNEC).

Lin Wu

e13125

Oncobox, gene expression-based second opinion system for predicting response to treatment in advanced solid tumors.

Elena Poddubskaya

e13143

Outcomes after adjuvant radiotherapy in breast cancer patients with and without germline mutations: A large, single-institutional experience.

Bhavana Sree Vangara Chapman

1502

Outcomes associated with rapid genetic testing for BRCA1 and BRCA2 at time of breast cancer diagnosis.

Kelly A. Metcalfe

1577

Performance and validation of a tumor mutation profiling, based on artificial intelligence annotation, to assist oncology decision making.

Miguel Mitne Neto

e13148

Psychosocial and clinical factors of probands impacting intrafamilial disclosure and uptake of genetic testing in families with BRCA1/2 or MMR gene mutations.

Pascal Pujol

e13151

Relationship of liver cancer with LRP1B or TP53 mutation and tumor mutation burden and survival.

Longrong Wang

1573

Screening of colorectal cancer (CRC) patients for lynch syndrome (LS) emphasizes the need for public insurance coverage of genetic testing: Results of a national program by the Hellenic Society of Medical Oncology (HeSMO).

Zacharenia Saridaki

e13141

Specific clonal expansion at disease progression (PD) in solid cancers pinpointed by cell free DNA analysis.

Elisa Frullanti

e13144

Suspected and confirmed germline variants from tumor-only somatic sequencing of 864 gastrointestinal malignancies.

Shivani Khanna

e13131

Ten-fold increase in genetic testing in pancreatic and metastatic prostate cancer with implementation of point of care (POC) testing.

Heather Symecko

1506

Thank you, next: The impact of next-generation sequencing in clinical decision making.

William Davis

e13136

The effect of the Affordable Care Act on genetic testing patterns and outcomes for inheritable cancer syndromes: A single institution experience.

Zhen Ni Zhou

e13157

Towards a screening test for cancer by circulating DNA analysis.

Alain R. Thierry

e13146

Tumor sequencing with germline genetic testing: Identification of patients with hereditary cancer and precision treatment eligibility.

Scott T. Michalski

1580

Unselected germline screening in pancreatic adenocarcinoma yields high rates of pathogenic and likely pathogenic variants (PV) in hereditary cancer susceptibility genes.

Carol Cremin

1582

Use of computer algorithms in the electronic health record to identify and triage primary care patients for hereditary evaluation.

Wendy Kohlmann

e13137

Validation of a comprehensive cancer genomic profiling assay based on massively parallel DNA sequencing.

Yuanyuan Hong

e13138

VONC: A solution for the clinical assessment of somatic genomic alterations.

Robert Kueffner

e13155