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Developmental Therapeutics and Tumor Biology (Nonimmuno)

2019 ASCO Annual Meeting

Sort by: title abstract no. first author
ABSTRACT TITLEFIRST AUTHORABSTRACT NO.
A novel CRISPR-directed gene editing method that catalyzes precise gene segment replacement in vitro enabling multiplex site-directed mutagenesis.

Gabi Tarcic

e14688

A phase Ia/Ib, open label, multicenter, dose-escalation study of BI 907828 (MDM2-p53 antagonist) in adult patients with advanced or metastatic solid tumors.

Curtis Robert Chong

TPS3166

A randomized, multicenter clinical trial to determine the efficacy and safety of pegfilgrastim (GEMA BIOTECH) compared to pegfilgrastim (Roche) for prevention of chemotherapy induced neutropenia in patients with breast cancer.

Martin Eduardo Richardet

3113

A retrospective analysis of venous thromboembolism trends in chemotherapy-induced anemia: Red blood cell transfusion versus erythrocyte stimulating agent (ESA) administration.

Emily Jane Bryer

e14685

Anticoagulants for the treatment of venous thromboembolism in patients with cancer: An updated pairwise and network meta-analysis of randomized trials.

Shima Sidahmed

e14692

Biofabricated tumor microenvironments for studying colorectal cancer in vitro and in vivo.

Mahesh Devarasetty

e14689

Cell-specific upregulation of lung “cancer signature genes” in the small airway epithelium of asymptomatic smokers.

Mahboubeh Rostami

3109

Changes of estrogen receptor, progesterone receptor and HER2 expression in breast cancer with/without neoadjuvant chemotherapy or endocrine therapy.

Shigeto Maeda

e14699

Clinical analysis of cancer associated venous thromboembolism in hospitalized patients with malignant solid tumors in real-world practices.

Da Jiang

e14686

Clinical, pathological and genetic predictors of patient-derived xenograft (PDX) engraftment in EGFR-mutated lung adenocarcinoma (LUAD).

Sebastiao N. Martins-Filho

3110

Clinical-relevant model of intraductal papillary mucinous neoplasm induced by ARID1A loss.

Tao Wei

e14696

Development and clinical validation of Lantern Pharma’s AI engine: Response algorithm for drug positioning and rescue (RADR).

Umesh Kathad

3114

Direct oral anticoagulants (DOAC) versus warfarin and enoxaparin in ovarian vein thrombosis.

Fahrettin Covut

e14698

Efficacy of entrectinib in patients (pts) with solid tumors and central nervous system (CNS) metastases: Integrated analysis from three clinical trials.

Salvatore Siena

3017

Feasibility and clinical impact of next-generation sequencing (NGS) in patients with stage IV or recurrent malignancies.

Fahrettin Covut

e14697

Genomic somatic alterations of human epidermal growth factor-2 (HER2) gene: A pan-cancer analysis.

Xinhua Zhu

3112

Host transcriptomic signatures associated with dysbiosis in a preclinical model of lung cancer.

Mariam El-Ashmawy

3107

Influence of deuterium-depleted water as a nutritive factor on the effectiveness of experimental chemotherapy in aging rats.

Alla I. Shikhlyarova

e14683

Integrative analyses of signaling and DNA damage repair pathways in patient-derived xenograft (PDX) models from NCI’s patient-derived models repository (PDMR).

Biswajit Das

3111

Measuring parameters of the cancer ecosystem for cancer ecological staging.

James R. Cunningham

e14684

Nonclinical endpoint assessment utilizing a digital vivarium cloud platform in an ovarian cancer xenograft model.

Chibueze Dominic Nwagwu

e14690

Phenotypic and functional characteristics of patient derived murine xenograft models.

Verena Imke Isabel Kiver

e14694

Prediction of olaparib sensitivity for variants of unknown significance in homologous repair genes.

Sandy Chevrier

3108

The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients.

Hong Zhu

e14681

The role of anticoagulants for the primary prophylaxis of venous thromboembolism in patients with malignancy: A systematic review and meta-analysis of randomized controlled trials.

Mahmoud Barbarawi

e14691

TrkA neurotrophin receptor and PI3K-Akt signaling involvement in cranial irradiation-induced memory deficit.

Shengjun Ji

e14679