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2019 ASCO Annual Meeting!

Session: Breast Cancer—Local/Regional/Adjuvant

Type: Poster Session

Time: Sunday June 2, 8:00 AM to 11:00 AM

Location: Hall A

Screening for cancer-related distress among women with newly diagnosed breast cancer (BC).

Local-Regional Therapy

Breast Cancer—Local/Regional/Adjuvant

2019 ASCO Annual Meeting

Abstract No:

Poster Board Number:
Poster Session (Board #59)

J Clin Oncol 37, 2019 (suppl; abstr 567)

Author(s): Lauren Z. Rynar, Kristen B. Wendell, Patricia B. Mumby, Kathy S. Albain, Patricia A. Robinson, Hanh P. Mai, Cathy Grace-Louthen, Shelly S. Lo; Loyola University Medical Center, Maywood, IL; Loyola University Chicago Stritch School of Medicine, Cardinal Bernardin Cancer Center, Maywood, IL

Abstract Disclosures


Background: The Loyola University Chicago Cardinal Bernardin Cancer Center multidisciplinary Breast Oncology Center evaluates new patients (pts) for cancer-related distress using a needs-based screening tool, in accordance with Commission on Cancer (CoC) Standard 3.2. Identifying distress among newly diagnosed pre-surgical and pre-neoadjuvant pts allows for comprehensive treatment planning and establishment of a baseline for repeated assessments. Methods: Pts with newly diagnosed BC between May 2017 and June 2018 completed the “Patient Screening Questions for Supportive Care” (Coleman Supportive Oncology Collaborative, 2017), a consolidated screening tool based on validated instruments (NCCN Distress, PHQ-4, PROMIS), prior to initial provider visit. Cancer staging, demographics, and supportive oncology referrals were obtained from medical records. Descriptive statistics and chi-square were used. Results: 100 pts aged 30-94 (mean(SD) = 61.56(12.03)) completed the screening tool; 14.9% had Stage 0, 43.6% Stage I, 34.0% Stage II, 3.2% Stage III, and 4.3% Stage IV disease. 39% of pts screened positive for anxiety on the PHQ-4, and over 20% for depression. Anxiety was associated with cancer stage (X2(df) = 12.20(4), p = .016). The most common practical concerns included living alone (19%), issues with work/school (16%), and paying for medical care (12%). Common physical concerns included difficulty with sleep (40%) and concentration/memory (17%), and tingling hands or feet (14%). Poor sleep was associated with depression (X2(df) = 6.50(1), p = .011) and anxiety (X2(df) = 7.17(1), p < .01). 57.7% reported at least "a little bit" of fatigue and 17.7% reported moderate to very severe pain. Nearly all pts wanted to better understand their diagnosis (87.8%), prognosis (87.8%), or treatment (91.8%). Conclusions: Pts with newly diagnosed, early stage BC experience high levels of physical and emotional distress at the earliest point in the treatment trajectory. This study captures BC patients at a unique time point and provides support for conducting routine screening for supportive oncology needs at initiation of care. Further studies should reassess needs sequentially to determine changes across the care continuum.

Other Abstracts in this Sub-Category:


1. Patient-reported outcomes (PROs) in NRG oncology/NSABP B-39/RTOG 0413: A randomized phase III study of conventional whole breast irradiation (WBI) versus partial breast irradiation (PBI) in stage 0, I, or II breast cancer.

Meeting: 2019 ASCO Annual Meeting Abstract No: 508 First Author: Patricia A. Ganz
Category: Breast Cancer—Local/Regional/Adjuvant - Local-Regional Therapy


2. Association between tumor biology and occult lymph node metastases before and after primary neoadjuvant therapy (NAT) for patients with early breast cancer.

Meeting: 2019 ASCO Annual Meeting Abstract No: 518 First Author: Hans-Christian Kolberg
Category: Breast Cancer—Local/Regional/Adjuvant - Local-Regional Therapy


3. A prospective validation cohort study of a prediction model on non-sentinel lymph node involvement in early breast cancer.

Meeting: 2019 ASCO Annual Meeting Abstract No: 559 First Author: Xingfei Yu
Category: Breast Cancer—Local/Regional/Adjuvant - Local-Regional Therapy