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Attend this session at the
2018 ASCO Annual Meeting!


Session: Cancer Prevention, Hereditary Genetics, and Epidemiology

Type: Poster Session

Time: Saturday June 2, 1:15 PM to 4:45 PM

Location: Hall A


Session: Cancer Prevention, Hereditary Genetics, and Epidemiology

Type: Poster Discussion Session

Time: Saturday June 2, 4:45 PM to 6:00 PM

Location: S404

Nutrition assessment among men undergoing genetic counseling for inherited prostate cancer: A teachable moment.

Sub-category:
Cancer Prevention

Category:
Cancer Prevention, Hereditary Genetics, and Epidemiology

Meeting:
2018 ASCO Annual Meeting

Abstract No:
1519

Poster Board Number:
Poster Discussion Session (Board #90)

Citation:
J Clin Oncol 36, 2018 (suppl; abstr 1519)

Author(s): Veda N. Giri, Michael Bruneau, Elias Obeid, Christa Smaltz, Brandy-Joe Milliron; Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA; Drexel University, Philadelphia, PA; Fox Chase Cancer Center, Philadelphia, PA; Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA

Abstract Disclosures

Abstract:

Background: Genetic counseling (GC) for men with or at-risk for prostate cancer (PCA) is growing with advancements in genetic testing (GT). GC provides a unique opportunity to promote a healthy lifestyle and is understudied in men. We conducted a targeted dietary analysis of men with or at-risk for PCA who have undergone GC and GT in the Genetic Evaluation of Men (GEM) study at two academic centers. Methods: GEM participants completed a structured lifestyle questionnaire (QA) which included dietary behaviors. QA included frequency of consuming six different types of foods (rich in vitamins C, A and D, cruciferous vegetables, rich in lycopene, smoked and/or salted meats) and daily servings for specific food groups (red meat, seafood, chicken, legumes/other protein sources, vegetables, fruit, grains, milk products, foods high in saturated fat) and alcohol. Diet intake was compared to USDA’s dietary recommendations for cancer survivorship. Distributions of dietary consumption were assessed by PCA status, PCA aggressiveness (Gleason > 7, T3, or metastatic disease), family history (FH), and body mass index (BMI) with Chi-Square contingency analyses and adjusted residuals (adj resid). Alpha levels were set a priori at p < .05. Results: Self-reported dietary data among men with PCA (n = 239) and at-risk for PCA (n = 81) who underwent GC was included. Overall, 84% were overweight/obese per CDC guidelines. Consumption of Vitamin C 1-2 times per week was significantly lower among men with aggressive PCA (adj resid = -1.9) vs. less aggressive PCA (adj resid = 1.9). Men with aggressive PCA also reported eating more red meat vs less aggressive PCA (p = 0.011). A higher percentage of men with aggressive PCA and higher weight did not meet the recommended guideline for vegetables (p = 0.047) and red meat (p = 0.015) than expected per contingency analyses. Conclusions: In this sample, specific dietary patterns were associated with aggressive PCA. A high proportion of men receiving GC for inherited PCA were overweight and/or obese, affording a teachable moment for lifestyle intervention. Key focus areas to develop diet intervention include consumption of less red meat and more vegetables among men at-risk or in survivorship.

 
Other Abstracts in this Sub-Category:

 

1. Low-fat dietary pattern and all cancer mortality in the Women's Health Initiative (WHI) randomized trial.

Meeting: 2018 ASCO Annual Meeting Abstract No: 1500 First Author: Rowan T. Chlebowski
Category: Cancer Prevention, Hereditary Genetics, and Epidemiology - Cancer Prevention

 

2. Adapted physical activity and recommendations for second cancers prevention for adolescents and young adults with cancer.

Meeting: 2018 ASCO Annual Meeting Abstract No: 1518 First Author: Julien Carretier
Category: Cancer Prevention, Hereditary Genetics, and Epidemiology - Cancer Prevention

 

3. Value of EGD for gastric cancer surveillance in patients with hereditary non-polyposis colorectal cancer (HNPCC) or Lynch syndrome (LS).

Meeting: 2018 ASCO Annual Meeting Abstract No: 1522 First Author: Swetlana Ladigan
Category: Cancer Prevention, Hereditary Genetics, and Epidemiology - Cancer Prevention

 

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