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Publication-only abstracts (abstract number preceded by an "e"), published in conjunction with the 2018 ASCO Annual Meeting but not presented at the Meeting, can be found online only.

Social disparities and patients’ attitudes are associated with lower rates of cervical cancer screening in Brazil: Results of EVITA study (LACOG 0215).

Sub-category:
Cervical Cancer

Category:
Gynecologic Cancer

Meeting:
2018 ASCO Annual Meeting

Abstract No:
e17510

Citation:
J Clin Oncol 36, 2018 (suppl; abstr e17510)

Author(s): Angelica Nogueira Rodrigues, Andreia Cristina de Melo, Aknar Calabrich, Eduardo Cronemberger, Kátia Luz Torres, Fernanda Damian, Rachel Jorge Dino Cossetti Leal, Carla Rameri Alexandre Silva De Azevedo, Allex Jardim da Fonseca, Yeni Verónica Neron, Joao Soares Nunes, André Lopes, Felipe Thome, Renato Leal, Giuliano Santos Borges, Arthur Ferreira da Silva, Matheus Füehr Rodrigues, Facundo Zaffaroni, Gustavo Werutsky, Fernando C. Maluf; Federal University of Minas Gerais Brazil and Brazilian Group of Gynecologic Oncology, Belo Horizonte, Brazil; Instituto Nacional do Câncer (INCA), Brazilian Group of Gynecological Oncology (EVA), Rio De Janeiro, Brazil; Clinica AMO, Brazilian Group of Gynecological Oncology (EVA), Salvador, Brazil; Centro Regional Integrado de Oncologia, Brazilian Group of Gynecological Oncology (EVA), Fortaleza, Brazil; FCECON - Amazonas, Brazilian Group of Gynecological Oncology (EVA), Manaus, Brazil; Centro de Pesquisa em Oncologia, Brazilian Group of Gynecological Oncology (EVA), Porto Alegre, Brazil; Hospital Aldenora Bello, Brazilian Group of Gynecological Oncology (EVA), São Luís, Brazil; Instituto de Medicina Integral Prof. Fernando Figueira - IMIP, Brazilian Group of Gynecological Oncology (EVA), Recife, Brazil; Hospital Geral de Roraima, Brazilian Group of Gynecological Oncology (EVA), Boa Vista, Brazil; Centro de Pesquisas Oncológicas-CEPON, Brazilian Group of Gynecological Oncology (EVA), Florianopolis-SC, Brazil; Hospital Erasto Gaertner, Brazilian Group of Gynecological Oncology (EVA), Curitiba, Brazil; Instituto Brasileiro de Controle do Câncer, Brazilian Group of Gynecological Oncology (EVA), São Paulo, Brazil; Hospital Sao Vicente de Paulo, Brazilian Group of Gynecological Oncology (EVA), Passo Fundo, Brazil; Hospital Universitário Walter Cantídio, Brazilian Group of Gynecological Oncology (EVA), Fortaleza, Brazil; Centro de Novos Tratamentos Itajai/Hospital Santo Antonio, Brazilian Group of Gynecological Oncology (EVA), Itajai, Brazil; Latin American Cooperative Oncology Group (LACOG), Porto Alegre, Brazil; Latin American Cooperative Oncology Group, Porto Alegre, Brazil; Hospital Beneficência Portuguesa de São Paulo e Hospital Israelita Albert Einstein, Brazilian Group of Gynecological Oncology (EVA), São Paulo, Brazil

Abstract Disclosures

Abstract:

Background: Cervical cancer (CC) is the fourth most common malignancy in women worldwide and around 85% of the cases are currently diagnosed in underdeveloped countries. Effective screening with Pap smear and HPV test can reduce the incidence of CC in about 90%. In Brazil, few retrospective/cancer registry studies have described screening patterns previous to CC diagnosis. We aim to assess the screening rates in the major CC study in Brazil (EVITA). Methods: Prospective, observational study, within 16 sites representing the five Brazilian regions. Main eligibility criteria were: ³18 years-old, stage I to IV invasive CC and signed informed consent. Data was collected during medical visits and medical charts. Results are expressed as mean (± SD) and relative frequencies. Chi-square and t tests were used for comparisons. Results: A total of 631 patients were enrolled from January 2016 to November 2017. Mean age at diagnosis was 49.3y (±13.9). Stage I, II, III and IV CC was diagnosed in 12.8%, 35.2%, 37.9% and 10.1% pts, respectively. 87.5% pts had a pap test performed at least once in lifetime. Lower educational level and income, and not having a stable partner were associated with not performing CC screening (Table 1); age, health insurance and alcohol and smoking status were analyzed, but no significant association has been found. The most frequent reasons reported by patients not to perform pap test were unwillingness (46.9%), shame or embarrassment (19.7%) and lack of knowledge (19.7%). Conclusions: Lower CC screening rate is associated with social disparities, as lower income and educational levels. Of note, we identify that unwillingness is a main reason not to perform screening test. CC screening access along with awareness campaigns must be a governmental priority, specially focused on the needy population.

Performed pap test
P
Yes (n = 537)No (n = 77)
Education
    Illiterate83.1%16.9%< .001
    ≤ 8y83.7%16.3%
    > 9y96.2%3.8%
Stable partner
    Yes91.1%8.9%.002
    No82.5%17.5%
Household income*
    No income72.0%28.0%< .001
    Less than 1 MW78.0%22.0%
    1-2 MW88.5%11.5%
    > 1-2 MW96.8%7.8%
Remunerated activity
    Yes91.2%8.8%.034
    No85.3%14.7%

* MW: minimum wage in Brazil (about US$ 270)

 
Other Abstracts in this Sub-Category:

 

1. Outcomes and costs of open, robotic, and laparoscopic radical hysterectomy for stage IB1 cervical cancer.

Meeting: 2018 ASCO Annual Meeting Abstract No: 5502 First Author: Daniel Jacob Margul
Category: Gynecologic Cancer - Cervical Cancer

 

2. Antitumor activity and safety of pembrolizumab in patients with advanced recurrent ovarian cancer: Interim results from the phase 2 KEYNOTE-100 study.

Meeting: 2018 ASCO Annual Meeting Abstract No: 5511 First Author: Ursula A. Matulonis
Category: Gynecologic Cancer - Cervical Cancer

 

3. Pembrolizumab treatment of advanced cervical cancer: Updated results from the phase 2 KEYNOTE-158 study.

Meeting: 2018 ASCO Annual Meeting Abstract No: 5522 First Author: Hyun Cheol Chung
Category: Gynecologic Cancer - Cervical Cancer

 

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