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2018 ASCO Annual Meeting!


Session: Head and Neck Cancer

Type: Poster Session

Time: Saturday June 2, 1:15 PM to 4:45 PM

Location: Hall A

Impact of patient symptoms and caregiver tasks on psychological distress in caregivers for head and neck cancer (HNC).

Sub-category:
Local-Regional

Category:
Head and Neck Cancer

Meeting:
2018 ASCO Annual Meeting

Abstract No:
6070

Poster Board Number:
Poster Session (Board #58)

Citation:
J Clin Oncol 36, 2018 (suppl; abstr 6070)

Author(s): Emily Castellanos, Mary S. Dietrich, Nancy L. Wells, Stewart M. Bond, Karen L. Schumacher, Barbara A. Murphy; Vanderbilt University Medical Center, Nashville, TN; Department of Biostatistics, Schools of Medicine and Nursing, Vanderbilt University Medical Center, Nashville, TN; Boston College Connell School of Nursing, Boston, MA; University of Nebraska Medical Center, Omaha, NE

Abstract Disclosures

Abstract:

Background: Caregiver support for HNC patients affects clinical outcomes including survival. Psychological distress in caregivers may impair the quality of support they provide. The impact of patient symptom burden and caregiver tasks on caregiver psychological distress is unknown. Methods: Patient symptom burden was assessed with the Vanderbilt Head and Neck Symptom Survey 2.0 (VHNSS 2.0; 10 domains, 3 single items). Caregiver task burden was assessed with the Caregiver Task Inventory (CTI; 11 domains), and quantified as task number and task difficulty/distress. Psychological distress was measured with the Profile of Mood States short form (POMS-SF). Two-step clustering analysis was used to independently generate clusters of caregiver distress, caregiver task burden, and patient symptom burden. Chi-Square and logistic regressions were used to test for associations of the resultant clusters of task burden and patient symptoms with caregiver distress. Results: 89 HNC patient-caregiver dyads were included. Patients were mostly male (77%) and Caucasian (88%). Median time since diagnosis was 3.7 months (IQR 2–7); 90% received combined modality therapy. Caregivers were mostly Caucasian (92%), female (85%) and spouses (80%). We found two caregiver clusters of psychological distress (40% mod-high, 60% low), and two clusters of caregiver task scores (40% mod-high, 60% low). Similarly, two clusters of patient symptom burden were found: 51% mod-high, 49% low. Caregivers with mod-high task scores were more likely than low to report mod-high levels of psychological distress (71% vs. 24%, p < 0.001). Patients with mod-high symptom burden were more likely than low to have caregivers with mod-high psychological distress (55% vs. 23%, p = 0.005). No effect modification of patient symptom burden on the association between caregiver task and caregiver psychological distress was seen (p > 0.05). Conclusions: Psychological distress in HNC caregivers is associated more strongly with caregiver task scores than patient symptoms. Further work to define the caregiver and task characteristics that lead to psychological distress should inform future interventions to support caregivers and patients.

 
Other Abstracts in this Sub-Category:

 

1. Results of a randomized phase III study of nimotuzumab in combination with concurrent radiotherapy and cisplatin versus radiotherapy and cisplatin alone, in locally advanced squamous cell carcinoma of the head and neck.

Meeting: 2018 ASCO Annual Meeting Abstract No: 6000 First Author: Vijay Maruti Patil
Category: Head and Neck Cancer - Local-Regional

 

2. Definitive cetuximab-based (CRT-CX) vs. non-cetuximab based chemoradiation (CRT) in older patients with squamous cell carcinoma of the head and neck (HNSCC): Analysis of the SEER-Medicare linked database.

Meeting: 2018 ASCO Annual Meeting Abstract No: 6001 First Author: Dan Paul Zandberg
Category: Head and Neck Cancer - Local-Regional

 

3. Treatment deintensification to surgery only for stage I human papillomavirus-associated oropharyngeal cancer.

Meeting: 2018 ASCO Annual Meeting Abstract No: 6003 First Author: John David Cramer
Category: Head and Neck Cancer - Local-Regional

 

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